Here’s a timeline I created for the current storyline when it was about halfway through. Sometimes it’s good to visualize things just to make sure they work out the way you need them to – especially in a ticking time bomb type situation. The speed of the Hood’s secondary hull was calculated as something realistically attainable that would get her to at least the equivalent of a medium Earth orbit when the pod ruptured. That would probably be the bare minimum safe distance if you accept that the Enterprise was in low orbit when it was hit by the shock waves produced by a much smaller portion of antimatter in Obsession.
This is excellent, James-Blish-level thinking. Thank you for working this out!